SCHEMBL27049351

SCHEMBL27049351

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5cccc(-c6ccc(-c7nc8ccccc8s7)cc6)c5)cc4)n3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 6/20 0.60
▸ MMP9 P14780 3/20 0.60
▸ MMP8 P22894 3/20 0.60
▸ RAB9A P51151 7/20 0.56
▸ KDM4E B2RXH2 5/20 0.56
▸ MAPT P10636 4/20 0.56
▸ NPC1 O15118 4/20 0.56
▸ LMNA P02545 3/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ GLA P06280 2/20 0.56
▸ GAA P10253 2/20 0.56
▸ NFKB1 P19838 4/20 0.56
▸ NFKB2 Q00653 4/20 0.56
▸ RELA Q04206 4/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ PAX8 Q06710 1/20 0.56
▸ NOD2 Q9HC29 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27049348 0.95 RAB9A (0.61) APPMMP9MMP8RAB9AKDM4E
SCHEMBL27258689 0.94 APP (0.54) APPMMP9MMP8RAB9AKDM4E
SCHEMBL19369706 0.92 RAB9A (0.65) APPMMP9MMP8RAB9AKDM4E
SCHEMBL27049229 0.91 RAB9A (0.53) APPMMP9MMP8RAB9AKDM4E
SCHEMBL24514780 0.91 APP (0.72) APPMMP9MMP8RAB9AKDM4E
SCHEMBL17701240 0.91 RAB9A (0.67) APPMMP9MMP8RAB9AKDM4E
SCHEMBL13067565 0.91 APP (0.72) APPMMP9MMP8RAB9AKDM4E
SCHEMBL13067470 0.90 APP (0.56) APPMMP9MMP8RAB9AKDM4E
SCHEMBL27049375 0.90 RAB9A (0.58) APPMMP9MMP8RAB9AKDM4E
SCHEMBL27049208 0.90 RAB9A (0.54) APPMMP9MMP8RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 — — US disclosed
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, L3MBTL4, PIEZO1 APP 2789/4885MMP9 746/4885MMP8 3271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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