SCHEMBL2705280

SCHEMBL2705280

CC(CC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGD P52209 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CYP2D6 P10635 1/20 0.35
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
NOS1 P29475 2/20 0.34
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
AAK1 Q2M2I8 1/20 0.33
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CACNA2D1 P54289 2/20 0.32
CACNB3 P54284 1/20 0.32
CACNA1C Q13936 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2351263 1.00 PGD (0.35) PGDCA1CA2CA7CYP2D6
SCHEMBL7181932 1.00 PGD (0.35) PGDCA1CA2CA7CYP2D6
SCHEMBL13007214 0.84 TDP1 (0.44) CA1CA2CA7CYP2D6MEN1
SCHEMBL7277806 0.84 CYP2D6 (0.32) PGDCA1CA2CA7CYP2D6
SCHEMBL10703266 0.83 CYP2D6 (0.46) CA1CA2CA7CYP2D6KMT2A
SCHEMBL12526882 0.83 CYP2D6 (0.46) CA1CA2CA7CYP2D6KMT2A
SCHEMBL28052779 0.80 CYP2D6 (0.32) CA1CA2CA7CYP2D6MEN1
SCHEMBL28052674 0.80 CYP2D6 (0.32) CA1CA2CA7CYP2D6MEN1
SCHEMBL27891039 0.80 CYP2D6 (0.32) CA1CA2CA7CYP2D6MEN1
SCHEMBL29943608 0.80 TDP1 (0.44) PGDCA1CA2CA7CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114276244-B Preparation method of carboxylic acid compound and metal salt derivative thereof 苏州汉酶生物技术有限公司 2024-02-27 CN claimed
JP-10298142-A None JP disclosed
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2026-04-07 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-4031521-B1 CARBONATE CONTAINING LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-12-24 EP disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2025-07-17 US disclosed
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-06-10 US disclosed
US-12312293-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-05-27 US disclosed
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-04-01 US disclosed
CN-100441594-C Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction AVENTIS PHARMA GMBH (DE) 2008-12-10 CN disclosed
CN-101090894-A Macrocyclic compounds and compositions useful as BACE inhibitors NOVARTIS AG (CH) 2007-12-19 CN disclosed
CN-101087820-A Polymer composition, plastic optical fiber, plastic optical cable, and method for producing plastic optical fiber MITSUBISHI RAYON CO (JP) 2007-12-12 CN disclosed
US-7186741-B2 Neurotensin active 2,3,diaryl-pyrazolidine derivatives SOLVAY PHARMACEUTICALS B.V. (NL) 2007-03-06 US disclosed
US-7186741-B2 Neurotensin active 2,3,diaryl-pyrazolidine derivatives SOLVAY PHARMACEUTICALS B.V. (NL) 2007-03-06 US disclosed
CN-1775801-A Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction AVENTIS PHARMA GMBH (DE) 2006-05-24 CN disclosed
CN-1237075-C Low molecular weight peptide derivatives as inhibitors of laminin/nidogen interaction AVENTIS PHARMA GMBH (DE) 2006-01-18 CN disclosed
WO-2003078400-A1 NEUROTENSIN ACTIVE 2,3-DIARYL-PYRAZOLIDINE DERIVATIVES SOLVAY PHARMACEUTICALS B.V. (NL) 2003-09-25 WO disclosed
CN-1342167-A Low molecular weight peptide derivatives as inhibitors of laminin/nidogen interaction AVENTIS PHARMA GMBH (DE) 2002-03-27 CN disclosed
JP-H10298142-A PURIFICATION OF 4-TERTIARY-BUTYL METHYLSUCCINATE MITSUBISHI RAYON CO LTD 1998-11-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 PGD 3993/4885CA1 4349/4885CA2 4394/4885
US-12312293-B2 Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents PLTP, LNPK, PLIN3 PGD 3170/4885CA1 4771/4885CA2 4841/4885
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents LNPK, PCTP, PLTP PGD 3919/4885CA1 1170/4885CA2 515/4885
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 PGD 3993/4885CA1 4349/4885CA2 4394/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 PGD 4606/4885CA1 3115/4885CA2 2269/4885
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 PGD 3993/4885CA1 4349/4885CA2 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.