Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119514 | 0.82 | MYC (0.39) | AKR1C2AKR1C1CSNK2A1KDM4ENOTUM | |
| SCHEMBL14363157 | 0.79 | PKM (0.55) | CSNK2A1KDM4EHPGDALDH1A1PTGS1 | |
| SCHEMBL23858450 | 0.78 | ALDH1A1 (0.46) | AKR1C2AKR1C1CSNK2A1KDM4EHPGD | |
| SCHEMBL1505292 | 0.78 | CSNK2A1 (0.50) | CSNK2A1KDM4ENOTUMHPGDHSD17B10 | |
| SCHEMBL27051511 | 0.77 | GLRA3 (0.42) | AKR1C2AKR1C1DHODHKMO | |
| SCHEMBL5029492 | 0.75 | CSNK2A1 (0.58) | AKR1C2AKR1C1CSNK2A1KDM4ETHRB | |
| SCHEMBL25564616 | 0.74 | CSNK2A1 (0.44) | AKR1C2AKR1C1CSNK2A1KDM4EHMGB1 | |
| SCHEMBL1970631 | 0.72 | ALB (0.52) | AKR1C2AKR1C1KDM4EHMGB1HPGD | |
| SCHEMBL3946987 | 0.72 | CFD (0.50) | AKR1C2AKR1C1 | |
| SCHEMBL122472 | 0.70 | HMGB1 (0.62) | AKR1C2AKR1C1CSNK2A1KDM4EHMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240027903-A1 | Resist Material And Patterning Process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240027903-A1 | Resist Material And Patterning Process | LBR, HNRNPU, EWSR1 | AKR1C2 4198/4885AKR1C1 4387/4885CSNK2A1 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.