Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119249 | 0.84 | SOS1 (0.40) | KDM4ENOTUMKCNK3KCNK9ALPL | |
| SCHEMBL27053038 | 0.82 | AKR1C2 (0.43) | KDM4ECSNK2A1NOTUMFABP4FABP5 | |
| SCHEMBL1505292 | 0.80 | CSNK2A1 (0.50) | MYCKDM4ECSNK2A1NOTUMHSD17B10 | |
| SCHEMBL23858450 | 0.77 | ALDH1A1 (0.46) | KDM4ECSNK2A1HSD17B10TSHRUSP2 | |
| SCHEMBL27256589 | 0.76 | KDM4E (0.54) | MYCKDM4ELCKFYNCSNK2A1 | |
| SCHEMBL20763063 | 0.74 | PGK1 (0.40) | NOTUMKMO | |
| SCHEMBL3946987 | 0.74 | CFD (0.50) | AKR1C2AKR1C1 | |
| SCHEMBL3925812 | 0.73 | TAS2R14 (0.43) | KDM4EHSD17B10TSHRUSP2ALDH1A1 | |
| SCHEMBL16964824 | 0.73 | KDM4E (0.47) | MYCKDM4ELCKFYNCSNK2A1 | |
| Acetic Acid SCHEMBL28155949 | 0.73 | KDM4E (0.50) | MYCKDM4ELCKFYNCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012067663-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |