Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769759 | 1.00 | IRAK4 (0.40) | IRAK4PIM1NPC1RAB9AKCNH2 | |
| Bromide SCHEMBL27035319 | 0.99 | IRAK4 (0.40) | IRAK4PIM1NPC1RAB9AKCNH2 | |
| SCHEMBL27059609 | 0.86 | LRRK2 (0.42) | IRAK4PIM1 | |
| Hydrochloric Acid SCHEMBL27035229 | 0.85 | LRRK2 (0.41) | IRAK4PIM1 | |
| Bromide SCHEMBL27035540 | 0.85 | LRRK2 (0.41) | IRAK4PIM1 | |
| SCHEMBL27035288 | 0.84 | PARP1 (0.41) | MAP3K12CCNT1CDK9HTR6 | |
| SCHEMBL30769931 | 0.84 | PARP1 (0.41) | MAP3K12CCNT1CDK9HTR6 | |
| SCHEMBL27058632 | 0.80 | CDK9 (0.38) | MAP3K12CCNT1CDK9HTR6 | |
| Hydrochloric Acid SCHEMBL30769764 | 0.79 | CDK9 (0.37) | MAP3K12CCNT1CDK9HTR6 | |
| SCHEMBL24683422 | 0.77 | PARP1 (0.41) | PIM1CCNT1CDK9HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |