SCHEMBL2706567

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12446575	0.78	ESR1 (0.38)	CA6KDM4EHSD17B10CA9CA14
	SCHEMBL13053993	0.78	HSD17B10 (0.50)	CA1CA2ALDH1A1HPGDHSD17B10
	SCHEMBL3438830	0.78	ALOX15 (0.50)	ALOX15HPGDGAASNCA
	SCHEMBL9607652	0.78	HSD17B10 (0.50)	CA1CA2ALOX15PTGS2ALDH1A1
	SCHEMBL13406915	0.78	ALOX15 (0.50)	ALOX15KDM4EPOLBL3MBTL1ALDH1A1
	SCHEMBL12704789	0.78	ALDH1A1 (0.46)	CA1CA2ALOX15KDM4EPOLB
	SCHEMBL14609269	0.74	APP (0.43)	APPTRPA1CA1CA2CA4
	SCHEMBL10019233	0.73	TUBB1 (0.47)	APPCA1CA2ALOX5ALOX15
	SCHEMBL13040392	0.73	KDM4E (0.33)	KDM4EL3MBTL1ALDH1A1TDP1MAPT
	SCHEMBL12024944	0.73	MAOB (0.55)	TRPA1CA1CA2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.