Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270305 | 0.88 | MEN1 (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL271720 | 0.88 | SCD (0.35) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL272431 | 0.87 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL271417 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL270926 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL271734 | 0.83 | PSEN1 (0.40) | ALDH1A1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL270507 | 0.81 | RORC (0.38) | ALDH1A1TSHRCYP1A2CYP2C19KMT2A | |
| SCHEMBL270581 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL271254 | 0.80 | GRM4 (0.38) | ALDH1A1SMN1; SMN2KMT2ALMNAL3MBTL1 | |
| SCHEMBL271717 | 0.80 | MMP1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | ALDH1A1 127/4885TSHR 1296/4885CYP1A2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.