Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27034269 | 0.82 | SFRP1 (0.42) | IDH1IDH2EHMT2SYK | |
| SCHEMBL26065733 | 0.81 | SYK (0.38) | IDH1IDH2SYKKRASACACB | |
| SCHEMBL25300699 | 0.76 | EHMT2 (0.46) | IDH1IDH2EHMT2SYKKRAS | |
| SCHEMBL30012480 | 0.76 | EHMT2 (0.46) | IDH1IDH2EHMT2SYKKRAS | |
| SCHEMBL27070110 | 0.75 | PDE9A (0.32) | IDH1IDH2 | |
| SCHEMBL26065392 | 0.74 | CYP11B2 (0.37) | SYKKRASACACBCYP11B2EIF2AK4 | |
| SCHEMBL26065251 | 0.74 | CYP11B2 (0.37) | SYKKRASACACBHDAC4CYP11B2 | |
| SCHEMBL25368335 | 0.74 | TRPV4 (0.42) | IDH1IDH2SYKCYP11B2 | |
| SCHEMBL30776008 | 0.73 | KRAS (0.42) | IDH1IDH2EHMT2KRASP2RX3 | |
| SCHEMBL27346552 | 0.72 | NR1H2 (0.38) | IDH1IDH2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020156-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-25 | — | — | WO | disclosed |