SCHEMBL2707321

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2707368	0.92	SMN1; SMN2 (0.47)	NPC1RAB9AMAPTSMN1; SMN2MEN1
	SCHEMBL2704604	0.86	NPC1 (0.44)	NPC1RAB9AROCK2MAPTSMN1; SMN2
	SCHEMBL2707199	0.86	NPC1 (0.46)	NPC1RAB9AHDAC6MAPTSMN1; SMN2
	SCHEMBL203602	0.86	NPC1 (0.50)	NPC1RAB9AMAPTSMN1; SMN2PKM
	SCHEMBL2320663	0.85	HDAC6 (0.47)	NPC1RAB9AHDAC6EPHX2ALOX5
	SCHEMBL202069	0.84	NPC1 (0.48)	NPC1RAB9AHDAC6MAPTSMN1; SMN2
	SCHEMBL201355	0.83	POLB (0.42)	NPC1RAB9AHDAC6MAPTSMN1; SMN2
	SCHEMBL4567016	0.83	RAB9A (0.43)	NPC1RAB9AROCK2MAPTSMN1; SMN2
	SCHEMBL201488	0.83	NPC1 (0.43)	NPC1RAB9AHDAC6MAPTSMN1; SMN2
	SCHEMBL201165	0.82	NPC1 (0.44)	NPC1RAB9AHDAC6ROCK2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.