SCHEMBL27075367

SCHEMBL27075367

CCO[Si](OCC)(OCC)c1ccccc1.CO[Si](CCCNCCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
DRD3 P35462 2/20 0.38
CHRM2 P08172 14/20 0.35
BCHE P06276 5/20 0.35
ACHE P22303 5/20 0.35
CHRM4 P08173 5/20 0.35
CHRM5 P08912 5/20 0.35
CHRM1 P11229 5/20 0.35
CHRM3 P20309 5/20 0.35
GRIN1 Q05586 4/20 0.35
GRIN2A Q12879 4/20 0.35
RECQL P46063 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
THPO P40225 1/20 0.35
SIGMAR1 Q99720 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6752944 0.86 LMNA (0.37)
SCHEMBL20574355 0.84 LMNA (0.41) DRD2DRD3CHRM2CHRM1CHRM3
SCHEMBL6687546 0.84 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL20954192 0.82 CHRM2 (0.40) DRD2DRD4DRD3CHRM2BCHE
SCHEMBL22472342 0.80 SIGMAR1 (0.53) SIGMAR1MEN1KMT2A
SCHEMBL20503705 0.77 CHRM2 (0.50) DRD4CHRM2BCHESIGMAR1MEN1
SCHEMBL2874122 0.77 TSHR (0.33) TP53TSHRPOLBSMN1; SMN2
SCHEMBL2257008 0.77 LMNA (0.36) TSHRMEN1KMT2A
SCHEMBL3623988 0.77 LMNA (0.36) TSHRMEN1KMT2A
SCHEMBL29900 0.77 LTA4H (0.37) TP53TSHRMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240034038-A1 A SOL-GEL COATING TO GIVE COATED SUBSTRATES BARRIER PROPERTIES AND METHOD OF APPLICATIONS THEREOF MILLIERY MANUEL (FR) 2024-02-01 US disclosed