SCHEMBL20574355

SCHEMBL20574355

CCCCCC[Si](OC)(OC)OC.CCO[Si](OCC)(OCC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
KCNH2 Q12809 2/20 0.34
SOAT1 P35610 1/20 0.33
NAAA Q02083 1/20 0.33
MPO P05164 1/20 0.32
LTA4H P09960 1/20 0.32
ABCB1 P08183 1/20 0.32
PPARA Q07869 1/20 0.31
EPHX1 P07099 3/20 0.31
EPHX2 P34913 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
MLNR O43193 1/20 0.31
NR1I2 O75469 1/20 0.31
ESR1 P03372 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
ADRB2 P07550 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRB1 P08588 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6752944 0.94 LMNA (0.37) LMNAMPOLTA4H
SCHEMBL8170696 0.91 KCNH2 (0.36) KCNH2SOAT1NAAALTA4HABCB1
SCHEMBL17969228 0.89 LMNA (0.45) LMNAKCNH2NAAAMPOLTA4H
SCHEMBL6687546 0.85 SMN1; SMN2 (0.31)
SCHEMBL27075367 0.84 DRD2 (0.38) CHRM2CHRM1DRD2CHRM3DRD3
SCHEMBL5396830 0.82 LMNA (0.40) LMNAMPOLTA4HEPHX2ALDH1A1
Benzene SCHEMBL28077932 0.82 LMNA (0.50) LMNAKCNH2PPARAHTTESR1
SCHEMBL19816444 0.82 LTA4H (0.38) LMNAKCNH2LTA4HALDH1A1HTT
SCHEMBL16597541 0.82 LMNA (0.35) LMNAKCNH2SOAT1NAAALTA4H
SCHEMBL5496697 0.81 LMNA (0.44) LMNAKCNH2NAAAMPOLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059740-B2 Glass article containing a coating with an interpenetrating polymer network Guardian Glass, LLC (US) 2021-07-13 US disclosed
US-20180346375-A1 Glass Article Containing a Coating with an Interpenetrating Polymer Network Guardian Glass, LLC 2018-12-06 US disclosed