Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27075654 | 0.84 | MAPK1 (0.48) | PDE5AMAPK1CHUKNPC1RAB9A | |
| SCHEMBL27075638 | 0.74 | HTR6 (0.45) | ALDH1A1POLBKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27075646 | 0.70 | BUB1 (0.52) | ALDH1A1MAPK1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13692589 | 0.68 | KMT2A (0.73) | LTA4HCYP1A2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL27075643 | 0.68 | BUB1 (0.52) | ALDH1A1KDM4ECHUKPIM1IDO1 | |
| SCHEMBL20870269 | 0.68 | KDM5A (0.57) | ALDH1A1POLBTSHRKDM4EHPGD | |
| SCHEMBL27075647 | 0.68 | BUB1 (0.53) | MAPK1HTTRAB9A | |
| SCHEMBL27075632 | 0.67 | CHUK (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2GABRP | |
| SCHEMBL27075645 | 0.67 | CHUK (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2GABRP | |
| SCHEMBL5605047 | 0.64 | LTA4H (0.82) | LTA4HCYP1A2CYP2D6ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891390-B1 | 3-substituted amino-2-arylpyrrolo[2,3-c]pyridines as CK2 inhibitors | King Faisal University (SA) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891390-B1 | 3-substituted amino-2-arylpyrrolo[2,3-c]pyridines as CK2 inhibitors | CSNK2A3, CSNK2A2, CSNK2A1 | LTA4H 2849/4885CYP1A2 3324/4885CYP2D6 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.