SCHEMBL2707644

SCHEMBL2707644

Nc1ccc(OC23CC4CC(C2)CC(Oc2ccc(N)c(O)c2)(C4)C3)cc1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.36
MAPT P10636 4/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
THRB P10828 2/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
XBP1 P17861 1/20 0.36
MMP2 P08253 1/20 0.35
MMP14 P50281 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR1 P03372 1/20 0.33
POLB P06746 2/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708874 0.88 ALDH1A1 (0.44) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL15380930 0.77 ALDH1A1 (0.44) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL2708447 0.77 ALDH1A1 (0.44) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL2709730 0.77 ALOX15 (0.36) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL2710593 0.74 ESR1 (0.48) GAAMEN1KMT2AALDH1A1HTT
SCHEMBL2746689 0.74
SCHEMBL28430332 0.73 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP3A4POLBTDP1
SCHEMBL2709915 0.72 GAA (0.34) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL11447106 0.72 SIGMAR1 (0.39) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL11448659 0.72 ALDH1A1 (0.37) GAAMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed