SCHEMBL2709730

SCHEMBL2709730

Nc1ccc(OC2(Oc3ccc(N)c(O)c3)C3CC4CC(C3)CC2C4)cc1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP3A4 P08684 1/20 0.36
MMP2 P08253 1/20 0.36
MMP14 P50281 1/20 0.36
GAA P10253 4/20 0.34
MAPT P10636 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
THRB P10828 2/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
XBP1 P17861 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709105 0.88 GAA (0.45) ALOX15HSD17B10GAAMAPTKDM4E
SCHEMBL2707644 0.77 GAA (0.36) ALOX15HSD17B10CYP3A4MMP2MMP14
SCHEMBL2709018 0.77 MMP2 (0.43) ALOX15HSD17B10CYP3A4MMP2MMP14
SCHEMBL2709915 0.76 GAA (0.34) ALOX15HSD17B10CYP3A4MMP2MMP14
SCHEMBL2706935 0.76 ALDH1A1 (0.41) CYP3A4GAAMAPTMEN1KMT2A
SCHEMBL2709017 0.74 GAA (0.36) ALOX15HSD17B10CYP3A4MMP2MMP14
SCHEMBL2710959 0.72 MEN1 (0.42) ALOX15HSD17B10CYP3A4GAAMAPT
SCHEMBL2710051 0.71 ALDH1A1 (0.45) KDM4EALDH1A1L3MBTL1POLBHSD11B1
SCHEMBL5086572 0.69 MEN1 (0.50) MMP2MMP14GAAMEN1KMT2A
SCHEMBL30040301 0.67 NR4A1 (0.61) ALOX15HSD17B10CYP3A4MMP2MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed