Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707781 | 1.00 | TTR (0.40) | TTRDPP4MAPTHCAR2CA12 | |
| SCHEMBL4458952 | 0.82 | ALDH1A1 (0.43) | CYP3A4ALDH1A1NPSR1USP2 | |
| SCHEMBL4458950 | 0.82 | ALDH1A1 (0.43) | CYP3A4ALDH1A1NPSR1USP2 | |
| SCHEMBL2426403 | 0.82 | USP2 (0.35) | CYP3A4ALDH1A1NPSR1USP2 | |
| SCHEMBL2706115 | 0.82 | NPSR1 (0.35) | CYP3A4ALDH1A1LMNANPSR1USP2 | |
| SCHEMBL2706119 | 0.82 | NPSR1 (0.35) | CYP3A4ALDH1A1LMNANPSR1USP2 | |
| SCHEMBL2707257 | 0.82 | NPSR1 (0.35) | CYP3A4ALDH1A1LMNANPSR1USP2 | |
| SCHEMBL4201125 | 0.79 | SLC6A19 (0.33) | ALDH1A1NPSR1USP2 | |
| SCHEMBL12048723 | 0.79 | SLC6A19 (0.33) | ALDH1A1NPSR1USP2 | |
| SCHEMBL11233392 | 0.78 | CYP2D6 (0.33) | MAPTALDH1A1LMNANPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2014-07-10 | — | — | US | disclosed |
| US-8409649-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2013-04-02 | — | — | US | disclosed |
| EP-2139841-B1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2012-05-02 | — | — | EP | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| EP-2139841-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008119197-A1 | 4-(2, 2, 3-TRIMETHYLCYCLOPENTYL) BUTANOIC ACID USED AS AN OFF-NOTE MASKING AGENT IN CONSUMABLES | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | TTR 2610/4885DPP4 751/4885MAPT 2636/4885 |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | TTR 2610/4885DPP4 751/4885MAPT 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.