Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | CTSG | P08311 | 3/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786199 | 0.99 | ALDH1A1 (0.45) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL168725 | 0.87 | RIPK1 (0.36) | ALDH1A1CNR2KMT2ACHRM2MAPT | |
| SCHEMBL19260219 | 0.84 | CA2 (0.46) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL28406017 | 0.84 | ALDH1A1 (0.42) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL29614441 | 0.81 | PPARG (0.36) | ALDH1A1PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9721468 | 0.80 | SCN1A (0.33) | PRSS1CTSGCTRB1CMA1TSHR | |
| SCHEMBL855518 | 0.79 | CYP2C19 (0.40) | ALDH1A1CNR2CTSLCTSBCTSS | |
| SCHEMBL14843728 | 0.77 | RIPK1 (0.30) | — | |
| SCHEMBL30478441 | 0.76 | ALDH1A1 (0.32) | ALDH1A1CYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL786580 | 0.76 | USP2 (0.42) | PRSS1CTSGCTRB1CMA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2436056-B1 | Electronic device comprising organic crosslinkable dielectrics and method of preparation thereof | BASF SE (DE) | 2016-08-03 | — | — | EP | disclosed |
| US-8853820-B2 | Crosslinkable dielectrics and methods of preparation and use thereof | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| EP-2436056-A1 | CROSSLINKABLE DIELECTRICS AND METHODS OF PREPARATION AND USE THEREOF | BASF SE (DE) | 2012-04-04 | — | — | EP | disclosed |
| WO-2010136385-A1 | CROSSLINKABLE DIELECTRICS AND METHODS OF PREPARATION AND USE THEREOF | BASF SE (DE) | 2010-12-02 | — | — | WO | disclosed |