SCHEMBL28406017

SCHEMBL28406017

CCCCCCC(C(=O)OOC(C)(C)C)C(C)(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
PRSS1 P07477 3/20 0.41
CTSG P08311 2/20 0.41
CTRB1 P17538 2/20 0.41
CMA1 P23946 2/20 0.41
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CNR2 P34972 1/20 0.39
LMNA P02545 1/20 0.38
HDAC8 Q9BY41 4/20 0.37
HDAC3 O15379 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP12 P39900 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786199 0.85 ALDH1A1 (0.45) ALDH1A1PRSS1CTSGCTRB1CMA1
SCHEMBL2707979 0.84 ALDH1A1 (0.43) ALDH1A1PRSS1CTSGCTRB1CMA1
SCHEMBL19260219 0.80 CA2 (0.46) ALDH1A1PRSS1CTSGCTRB1CMA1
SCHEMBL29614441 0.75 PPARG (0.36) ALDH1A1PRSS1CTSGCTRB1CMA1
SCHEMBL14680116 0.73 TSHR (0.46) ALDH1A1TSHRHSD17B10LMNA
SCHEMBL14680108 0.73 TSHR (0.46) ALDH1A1TSHRHSD17B10LMNA
SCHEMBL21925211 0.73 CA2 (0.50)
SCHEMBL168725 0.72 RIPK1 (0.36) ALDH1A1CNR2
Dodecane SCHEMBL12471263 0.72 TDP1 (0.77) ALDH1A1PRSS1CTSGCTRB1CMA1
SCHEMBL30081056 0.72 HSPD1 (0.49) ALDH1A1PRSS1CTSGCTRB1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111183188-A Molded article 古河电气工业株式会社 2020-05-19 CN disclosed