Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 9/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085076 | 0.93 | TYR (0.51) | TYRATMSLC5A2SLC5A1HTR6 | |
| SCHEMBL27084741 | 0.90 | HTR1D (0.56) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL26790992 | 0.90 | HTR1D (0.56) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL26790014 | 0.90 | HTR1D (0.56) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL27084824 | 0.89 | HTR1D (0.45) | HTR1DHTR3EHTR3BCYP1A2HTR1A | |
| SCHEMBL27085283 | 0.87 | HTR2A (0.52) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL27084910 | 0.86 | ATM (0.48) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL27084663 | 0.86 | HTR1A (0.57) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL27084989 | 0.85 | ATM (0.49) | TYRATMSLC5A2SLC5A1HTR1D | |
| SCHEMBL27084964 | 0.85 | HTR1D (0.52) | TYRATMSLC5A2SLC5A1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | COMPASS PATHFINDER LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | INMT, AANAT, HNMT | TYR 153/4885ATM 3022/4885SLC5A2 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.