Phenol

Phenol

SCHEMBL28023686

N#Cc1cccc(-c2ccccc2)c1.Oc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.57
SLC22A12 Q96S37 1/20 0.57
GABRG2 P18507 2/20 0.53
GABRB3 P28472 2/20 0.53
GABRA5 P31644 2/20 0.53
GABRA3 P34903 2/20 0.53
GABRA1 P14867 1/20 0.53
PTPN5 P54829 1/20 0.53
MMP3 P08254 3/20 0.50
HSD17B1 P14061 2/20 0.50
HSD17B2 P37059 2/20 0.50
CLK4 Q9HAZ1 1/20 0.50
KAT6A Q92794 1/20 0.50
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 1/20 0.48
ADORA2A P29274 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322948 0.90 MMP3 (0.63) XDHSLC22A12PTPN5MMP3HSD17B1
SCHEMBL29425207 0.90 GABRG2 (0.61) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL270874 0.90 GABRG2 (0.61) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL30165928 0.88 HSD17B1 (0.58) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL1029016 0.88 HSD17B1 (0.58) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL18411383 0.88 GABRG2 (0.59) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL18411368 0.88 GABRG2 (0.59) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL27787243 0.85 CLK4 (0.63) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL29511815 0.84 XDH (0.56) XDHSLC22A12GABRG2GABRB3GABRA5
SCHEMBL20396126 0.84 XDH (0.56) XDHSLC22A12GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104822800-B Double mesomorphic compounds and mesogenic media 默克专利股份有限公司 2018-03-30 CN disclosed
CN-105579555-A Compounds and mesogenic media MERCK PATENT GMBH 2016-05-11 CN disclosed
CN-104822800-A BImesogenic compounds and mesogenic media MERCK PATENT GMBH 2015-08-05 CN disclosed