Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98312 | 0.81 | TSHR (0.60) | TSHRALDH1A1TP53HPGDALOX15 | |
| SCHEMBL694036 | 0.81 | TDP1 (0.48) | TSHRALDH1A1HSD17B10RECQLTP53 | |
| SCHEMBL153943 | 0.80 | TSHR (0.67) | TSHRALDH1A1HSD17B10RECQLTP53 | |
| Methyl Alcohol SCHEMBL27778102 | 0.79 | TSHR (0.57) | TSHRALDH1A1TP53HPGDALOX15 | |
| SCHEMBL9177111 | 0.79 | TSHR (0.57) | TSHRALDH1A1TP53HPGDALOX15 | |
| Acetic Acid SCHEMBL11090541 | 0.79 | ALDH1A1 (0.68) | TSHRALDH1A1HSD17B10RECQLTP53 | |
| Hydrochloric Acid SCHEMBL7347939 | 0.79 | TSHR (0.57) | TSHRALDH1A1TP53HPGDALOX15 | |
| SCHEMBL28377201 | 0.79 | TSHR (0.41) | TSHRALDH1A1HSD17B10RECQLTP53 | |
| Acetic Acid SCHEMBL3959213 | 0.78 | TSHR (0.74) | TSHRALDH1A1HSD17B10TP53CYP3A4 | |
| Bicarbonate SCHEMBL28202106 | 0.78 | TSHR (0.74) | TSHRALDH1A1HSD17B10RECQLTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12638399-B2 | Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2026-05-26 | — | — | US | claimed |
| EP-4162266-B1 | METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE | ARCHER DANIELS MIDLAND CO (US) | 2025-06-25 | — | — | EP | claimed |
| US-20240060902-A1 | METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE | ARCHER DANIELS MIDLAND CO (US) | 2024-02-22 | — | — | US | claimed |
| EP-4162266-A1 | METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE | Archer Daniels Midland Company (US) | 2023-04-12 | — | — | EP | claimed |
| US-12638399-B2 | Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4162266-B1 | METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE | ARCHER DANIELS MIDLAND CO (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20240060902-A1 | METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE | ARCHER DANIELS MIDLAND CO (US) | 2024-02-22 | — | — | US | disclosed |
| EP-4162266-A1 | METHOD FOR DETERMINING TOTAL ALDEHYDES IN ONE OR MORE OF CRUDE 2,5-FURANDICARBOXYLIC ACID (FDCA), CRUDE TEREPHTHALIC ACID (TPA) AND ESTERS OF THESE | Archer Daniels Midland Company (US) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12638399-B2 | Method for determining total aldehydes in one or more of crude 2,5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA) and esters of these | FTO, AOC1, AOC2 | TSHR 1256/4885ALDH1A1 49/4885HSD17B10 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.