Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710593 | 0.92 | ESR1 (0.48) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL4991468 | 0.88 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL2707241 | 0.87 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL2709265 | 0.85 | KMT2A (0.48) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL5141163 | 0.83 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL2709018 | 0.82 | MMP2 (0.43) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL27845478 | 0.81 | LMNA (0.61) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL31544679 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL2706961 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL2707709 | 0.81 | MEN1 (0.38) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033142-A1 | BILE PREPARATIONS FOR COLORECTAL DISORDERS | YOO SEO HONG (US) | 2008-03-20 | — | — | WO | claimed |
| US-20070072828-A1 | Gastrointestinal disorders; antiulcer agents; adenomatous polyposis coli; a bile acid (7-ketolithocholic acid) | YOO SEO H | 2007-03-29 | — | — | US | claimed |
| WO-2008033142-A1 | BILE PREPARATIONS FOR COLORECTAL DISORDERS | YOO SEO HONG (US) | 2008-03-20 | — | — | WO | disclosed |
| US-20070072828-A1 | Gastrointestinal disorders; antiulcer agents; adenomatous polyposis coli; a bile acid (7-ketolithocholic acid) | YOO SEO H | 2007-03-29 | — | — | US | disclosed |