⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335441 | 0.81 | — | — | |
| SCHEMBL28681524 | 0.78 | TLR8 (0.39) | — | |
| SCHEMBL6647747 | 0.77 | — | — | |
| SCHEMBL930828 | 0.76 | TLR8 (0.40) | — | |
| Hydrochloric Acid SCHEMBL6049597 | 0.76 | TLR8 (0.38) | — | |
| SCHEMBL10685891 | 0.75 | CA2 (0.33) | — | |
| SCHEMBL10637978 | 0.75 | — | — | |
| SCHEMBL27949086 | 0.74 | LIPG (0.42) | — | |
| SCHEMBL9773323 | 0.74 | CES1 (0.40) | — | |
| SCHEMBL9710840 | 0.73 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186433-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | EPIVARIO, INC. | 2025-06-12 | — | — | US | disclosed |
| US-12133852-B2 | ACSS2 inhibitors and methods of use thereof | EPIVARIO, INC. (US) | 2024-11-05 | — | — | US | disclosed |
| CN-113710723-B | Use of functionalized alpha-angelicalactone | 汉高股份有限及两合公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114450127-B | Polishing pad employing polyamine and cyclohexanedimethanol curing agent | CMC材料有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118043372-A | Two-component (2K) compositions based on epoxy (meth) acrylate resins | 汉高股份有限及两合公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114787298-B | Two-component (2K) curable adhesive composition | 汉高股份有限及两合公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116601203-A | Two-component (2K) epoxy formulations | 汉高股份有限及两合公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-108789186-B | Method of manufacturing a chemical mechanical polishing layer with improved uniformity | 陶氏环球技术有限责任公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20220305010-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD. (IL) | 2022-09-29 | — | — | US | disclosed |
| CN-113980536-B | Formaldehyde absorption emulsion and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| EP-1362856-B1 | WATER-SOLUBLE TRIAZOLE FUNGICIDE | DAIICHI SANKYO CO LTD (JP) | 2008-09-10 | — | — | EP | disclosed |
| EP-0819000-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| US-5962499-A | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1999-10-05 | — | — | US | disclosed |
| CN-1184423-A | Nodulisporic acid derivatives | MERCK & CO INC (US) | 1998-06-10 | — | — | CN | disclosed |
| EP-0819000-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996029073-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-09-26 | — | — | WO | disclosed |
| EP-0042626-B1 | ANTICONVULSIVE COMPOSITIONS | NEW YORK UNIVERSITY (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4372974-A | Anticonvulsive compositions and method of treating convulsive disorders | NEW YORK UNIVERSITY (US) | 1983-02-08 | — | — | US | disclosed |
| US-4322440-A | Anticonvulsive compositions and method of treating convulsive disorders | NEW YORK UNIVERSITY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0042626-A2 | Anticonvulsive compositions | NEW YORK UNIVERSITY (US) | 1981-12-30 | — | — | EP | disclosed |