SCHEMBL27100766

SCHEMBL27100766

CC1(C)c2cc(S(N)(=O)=O)ccc2NC12C=Cc1cc(C(=O)c3ccc(F)cc3)ccc1O2

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.35
EPAS1 Q99814 6/20 0.35
CA1 P00915 6/20 0.33
CA2 P00918 6/20 0.33
CA9 Q16790 6/20 0.33
CA4 P22748 4/20 0.33
MAOA P21397 1/20 0.33
MEN1 O00255 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
CA12 O43570 2/20 0.32
CA7 P43166 2/20 0.32
CA14 Q9ULX7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27100765 0.92 PTGS2 (0.39) HIF1AEPAS1MEN1GFERKMT2A
SCHEMBL27100762 0.86 MEN1 (0.33) HIF1AEPAS1MEN1GFERKMT2A
SCHEMBL27100761 0.85 MEN1 (0.33) HIF1AEPAS1MEN1GFERKMT2A
SCHEMBL27100750 0.84 MAPT (0.34) HIF1AEPAS1MEN1GFERKMT2A
SCHEMBL27100755 0.83 ABCC9 (0.32) MEN1GFERKMT2AMAPK1
SCHEMBL27100799 0.82 TLK2 (0.33) HIF1AEPAS1MAPK1
SCHEMBL27100797 0.82 SIRT1 (0.33) MEN1GFERKMT2AMAPTMAPK1
SCHEMBL27100757 0.81 MEN1 (0.37) MEN1GFERKMT2AMAPT
SCHEMBL26779460 0.78 MEN1 (0.57) HIF1AEPAS1CA1CA2CA9
SCHEMBL27100763 0.77 MEN1 (0.37) MEN1GFERKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed