SCHEMBL27100797

SCHEMBL27100797

CC(C)(C)c1ccc2c(c1)C=CC1(Nc3ccc(C(=O)c4ccc(F)cc4)cc3C1(C)C)O2

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.33
TP53 P04637 1/20 0.32
GAA P10253 2/20 0.31
MAPT P10636 1/20 0.31
SRD5A2 P31213 1/20 0.30
RXFP1 Q9HBX9 2/20 0.30
NPC1 O15118 1/20 0.30
HSP90AA1 P07900 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
PTGS1 P23219 1/20 0.30
MAPK1 P28482 1/20 0.30
KDR P35968 1/20 0.30
MEN1 O00255 1/20 0.30
GFER P55789 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27100762 0.86 MEN1 (0.33) TP53RXFP1SMN1; SMN2ADORA3PTGS1
SCHEMBL27100799 0.85 TLK2 (0.33) GAARXFP1NPC1ADORA3PTGS1
SCHEMBL27100761 0.85 MEN1 (0.33) RXFP1ADORA3PTGS1MAPK1KDR
SCHEMBL27100750 0.84 MAPT (0.34) TP53GAAMAPTNPC1PKM
SCHEMBL27100765 0.83 PTGS2 (0.39) PTGS1MEN1GFERKMT2A
SCHEMBL27100755 0.83 ABCC9 (0.32) RXFP1SMN1; SMN2ADORA3PTGS1MAPK1
SCHEMBL27100757 0.82 MEN1 (0.37) TP53GAAMAPTNPC1RAB9A
SCHEMBL27100766 0.82 HIF1A (0.35) MAPTMAPK1MEN1GFERKMT2A
SCHEMBL27100809 0.79 HPGD (0.36) TP53MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL27100747 0.78 ALDH1A1 (0.34) MAPTNPC1RAB9ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed