Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27101050 | 0.86 | ALDH1A1 (0.50) | ALDH1A1NSD2NPC1MAPTMAPK1 | |
| SCHEMBL29712740 | 0.86 | ALDH1A1 (0.50) | ALDH1A1NSD2NPC1MAPTMAPK1 | |
| SCHEMBL27101037 | 0.85 | ALDH1A1 (0.51) | ALDH1A1NSD2NPC1MAPTMAPK1 | |
| SCHEMBL29417829 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NSD2NPC1MAPTMAPK1 | |
| SCHEMBL27101046 | 0.84 | OPRK1 (0.52) | ALDH1A1NSD2NPC1MAPTMAPK1 | |
| SCHEMBL18440746 | 0.83 | IRAK4 (0.43) | ALDH1A1NPC1MAPTMAPK1RAB9A | |
| SCHEMBL23185880 | 0.82 | ALDH1A1 (0.56) | ALDH1A1NSD2NPC1MAPTMAPK1 | |
| SCHEMBL29848392 | 0.81 | ALDH1A1 (0.55) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL4444780 | 0.81 | ALDH1A1 (0.55) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL31615767 | 0.81 | KIT (0.48) | NPC1MAPTRAB9AGPR119PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067645-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | LG CHEM, LTD. (KR) | 2024-02-29 | — | — | US | disclosed |
| CN-116615199-A | Heterocyclic compounds as diacylglycerol kinase inhibitors and uses thereof | 株式会社LG化学 | 2023-08-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067645-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | DGKA, DGKB, DGKK | ALDH1A1 2241/4885NSD2 2352/4885NPC1 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.