Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932127 | 0.90 | KDM4E (0.47) | SERPINE1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL321828 | 0.81 | ALDH1A1 (0.41) | MAPTMEN1KMT2APKMTDP1 | |
| SCHEMBL27701909 | 0.74 | MAPT (0.37) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL15067280 | 0.74 | MEN1 (0.72) | SERPINE1MAPTMEN1KMT2APKM | |
| SCHEMBL1931407 | 0.72 | MAPT (0.43) | MAPTMEN1KMT2ATDP1SIRT6 | |
| SCHEMBL16473318 | 0.71 | KDM4E (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL15094046 | 0.71 | RAB9A (0.42) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1056451 | 0.69 | KMT2A (1.00) | SERPINE1MAPTMEN1KMT2APKM | |
| SCHEMBL1954779 | 0.68 | MEN1 (0.72) | SERPINE1MAPTMEN1KMT2APKM | |
| SCHEMBL6096421 | 0.68 | MEN1 (0.74) | SERPINE1MAPTMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861403-B1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SA (FR) | 2012-05-02 | — | — | EP | disclosed |
| EP-1861403-A1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097625-A1 | NOVEL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-AVENTIS (FR) | 2006-09-21 | — | — | WO | disclosed |