Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709976 | 0.84 | MAPT (0.43) | MAPTRAB9AMAPK1GAAHTT | |
| SCHEMBL321828 | 0.79 | ALDH1A1 (0.41) | MAPTRAB9ANTRK1ALDH1A1KDM4E | |
| SCHEMBL2710132 | 0.74 | SERPINE1 (0.50) | MAPTRAB9AHTTALDH1A1HPGD | |
| SCHEMBL1931407 | 0.74 | MAPT (0.43) | MAPTRAB9AMAPK1GAAHTT | |
| SCHEMBL14927688 | 0.71 | NTRK1 (0.40) | MAPTRAB9AMAPK1HTTNTRK1 | |
| SCHEMBL16473318 | 0.69 | KDM4E (0.53) | MAPTRAB9AMAPK1GAAALDH1A1 | |
| SCHEMBL15094046 | 0.69 | RAB9A (0.42) | MAPTRAB9AMAPK1GAAHTT | |
| SCHEMBL322528 | 0.69 | DAPK3 (0.42) | MAPTRAB9AGAANTRK1ALDH1A1 | |
| SCHEMBL327387 | 0.67 | SLC2A1 (0.52) | RAB9AHTTALDH1A1KDM4EHPGD | |
| SCHEMBL2712093 | 0.66 | CDC25B (0.43) | MAPTGAAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102050821-A | Novel imidazo [1,5-a ] pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI AVENTIS | 2011-05-11 | — | — | CN | disclosed |
| CN-101160309-A | Novel imidazo [1, 5-a ] pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI AVENTIS (FR) | 2008-04-09 | — | — | CN | disclosed |