SCHEMBL2710595

SCHEMBL2710595

Nc1ccc(C23CC4CC(C2)CC(c2ccc(N)cc2Oc2cccc(O)c2)(C4)C3)c(Oc2cccc(O)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
LMNA P02545 2/20 0.34
PGR P06401 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA14 Q9ULX7 1/20 0.34
KMT2A Q03164 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
EIF2AK2 P19525 1/20 0.32
GSK3B P49841 1/20 0.32
ESR1 P03372 1/20 0.32
MEN1 O00255 1/20 0.32
MITF O75030 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408351 0.86 GRIN2D (0.39) ALDH1A1LMNAPGRKMT2AMEN1
SCHEMBL2709020 0.83 ALDH1A1 (0.36) ALDH1A1CA12CA1CA2CA7
SCHEMBL2748107 0.79 FAAH (0.31) ALDH1A1CA12CA1CA2CA7
SCHEMBL2709184 0.78 FAAH (0.39) ALDH1A1LMNAPGRTDP1KMT2A
SCHEMBL2706958 0.75 ALDH1A1 (0.36) ALDH1A1LMNAPGRTDP1KMT2A
SCHEMBL2710589 0.75 MMP2 (0.35) ALDH1A1LMNAPGRKMT2AESR1
SCHEMBL2710489 0.73 NCOA1 (0.45) ALDH1A1LMNAPGRTDP1KMT2A
SCHEMBL2709890 0.73 ALDH1A1 (0.42) ALDH1A1LMNAPGRTDP1KMT2A
SCHEMBL17506787 0.73 ALDH1A1 (0.50) ALDH1A1LMNACA12CA1CA2
SCHEMBL2708150 0.73 MEN1 (0.37) ALDH1A1LMNAPGRTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed