SCHEMBL27113182

SCHEMBL27113182

CNCC(=O)NCc1cccc(CNC(=O)OC(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GLS O94925 9/20 0.54
CYP3A4 P08684 1/20 0.46
BRD4 O60885 3/20 0.45
KDM4A O75164 1/20 0.45
CREBBP Q92793 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
ALDH1A1 P00352 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NAMPT P43490 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16181822 0.89 GLS (0.55) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL27113184 0.85 AOC3 (0.56) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL28211519 0.84 GLS (0.62) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL13853709 0.83 GLS (0.53) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL1165088 0.83 GLS (0.55) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL30069429 0.83 GLS (0.55) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL8342682 0.83 GLS (0.55) GLSBRD4KDM4ACREBBPCA1
SCHEMBL13981921 0.83 GLS (0.55) GLSCYP3A4BRD4KDM4ACREBBP
SCHEMBL14679374 0.83 KDM4E (0.49) GLSCYP3A4BRD4ALDH1A1
SCHEMBL3346015 0.82 GLS (0.54) GLSCYP3A4BRD4KDM4ACREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SLC7A1, ABCB11, SLC1A5 GLS 230/4885CYP3A4 1258/4885BRD4 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.