Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27117690 | 0.92 | S1PR1 (0.32) | S1PR1S1PR4S1PR3S1PR5SIGMAR1 | |
| SCHEMBL27119910 | 0.79 | DRD1 (0.33) | SIGMAR1 | |
| SCHEMBL27120160 | 0.76 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL25993969 | 0.75 | SLC6A2 (0.36) | — | |
| SCHEMBL27120066 | 0.73 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL25999425 | 0.72 | OPRK1 (0.30) | — | |
| SCHEMBL27120419 | 0.72 | S1PR1 (0.31) | S1PR1SIGMAR1 | |
| SCHEMBL27113705 | 0.71 | MMP1 (0.33) | S1PR1FAAH | |
| SCHEMBL25993020 | 0.70 | SLC6A2 (0.33) | — | |
| SCHEMBL26021674 | 0.69 | PDK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076650-B1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2024-02-28 | — | — | EP | disclosed |