Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.49 |
| ▸ | ABL1 | P00519 | 11/20 | 0.49 |
| ▸ | PRKCA | P17252 | 7/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 10/20 | 0.48 |
| ▸ | SRC | P12931 | 6/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27144622 | 0.87 | ABL1 (0.62) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27115894 | 0.85 | CAMK2D (0.60) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27115272 | 0.84 | PLK1 (0.47) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27116599 | 0.82 | ABL1 (0.62) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27115761 | 0.81 | PRKCA (0.51) | ABL1PRKCAPRKCDEGFRBCR | |
| SCHEMBL27144345 | 0.81 | SYK (0.49) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27145130 | 0.80 | PLK1 (0.51) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27115274 | 0.80 | CDK4 (0.50) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27115673 | 0.79 | ABL1 (0.44) | PLK1ABL1PRKCAPRKCDEGFR | |
| SCHEMBL27116134 | 0.78 | GSK3B (0.52) | PLK1ABL1BCRSRCCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | claimed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |