SCHEMBL2712341

SCHEMBL2712341

COc1ccc(-c2c3ccccc3c(-c3c(F)c(F)c(OC)c(F)c3F)c3cc(F)c(F)cc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.38
MAOB P27338 3/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ALOX5 P09917 1/20 0.36
ABL1 P00519 1/20 0.36
ABCB1 P08183 1/20 0.36
BCR P11274 1/20 0.36
ALDH1A1 P00352 5/20 0.36
HPGD P15428 5/20 0.36
KDM4E B2RXH2 5/20 0.36
MAPT P10636 5/20 0.36
LMNA P02545 3/20 0.36
ACACA Q13085 1/20 0.36
HTT P42858 1/20 0.36
SYK P43405 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2712750 0.93 ACHE (0.48) ACHEL3MBTL1MAOBCA1CA2
SCHEMBL2710059 0.93 ACHE (0.50) ACHEL3MBTL1ABCG2MAOBCA1
SCHEMBL2711840 0.90 PDE4B (0.40) ACHEABCG2ALDH1A1KDM4ETUBB4A
SCHEMBL2709441 0.89 MEN1 (0.40) ACHEMAOBCA1CA2ALDH1A1
SCHEMBL2710318 0.89 ACHE (0.43) ACHEL3MBTL1ABCG2MAOBCA1
SCHEMBL2712151 0.89 ACHE (0.47) ACHEL3MBTL1MAOBCA1CA2
SCHEMBL2712303 0.88 ALDH1A1 (0.43) L3MBTL1ALDH1A1HPGDKDM4EMAPT
SCHEMBL2711263 0.87 L3MBTL1 (0.36) ACHEL3MBTL1ABCG2ABCB1ALDH1A1
SCHEMBL2710023 0.87 ACHE (0.39) ACHEL3MBTL1ABCG2MAOBCA1
SCHEMBL2943357 0.87 ALDH1A1 (0.42) L3MBTL1ALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 ACHE 187/4885L3MBTL1 2477/4885ABCG2 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.