SCHEMBL27124181

SCHEMBL27124181

O=C(O)C(c1ccccc1Cl)C1CCCNC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.43
CPB2 Q96IY4 1/20 0.43
SLC6A2 P23975 8/20 0.40
SLC6A4 P31645 8/20 0.40
SLC6A3 Q01959 8/20 0.40
KCNH2 Q12809 3/20 0.40
KMT2A Q03164 1/20 0.39
RPLP1 P05386 1/20 0.39
RPLP0 P05388 1/20 0.39
RPS17 P08708 1/20 0.39
RPSA P08865 1/20 0.39
RPS2 P15880 1/20 0.39
RPL35A P18077 1/20 0.39
RPL7 P18124 1/20 0.39
RPL17 P18621 1/20 0.39
RPS4Y1 P22090 1/20 0.39
RPS3 P23396 1/20 0.39
RPS12 P25398 1/20 0.39
RPL13 P26373 1/20 0.39
RPL10 P27635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30491023 0.85 SLC6A3 (0.46) SLC6A2SLC6A4SLC6A3
SCHEMBL27132169 0.83 CPN1 (0.41) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL2788659 0.83 TAS1R3 (0.45) SLC6A3KMT2A
SCHEMBL27410776 0.81 CPN1 (0.49) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL10608107 0.81 OPRL1 (0.43) KMT2A
SCHEMBL5309381 0.81 SLC6A2 (0.46) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL27123836 0.78 CPN1 (0.39) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL16475935 0.73 CPN1 (0.47) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL31066542 0.72 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3CYP2D6
SCHEMBL18547184 0.72 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230416202-A1 Small Molecule Compounds and Compositions TELO THERAPEUTICS, INC. 2023-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230416202-A1 Small Molecule Compounds and Compositions TERT, TP53, EP300 CPN1 3920/4885CPB2 4075/4885SLC6A2 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.