Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27125986 | 1.00 | ALDH1A1 (0.44) | ALDH1A1DPP4ELANENPC1RAB9A | |
| SCHEMBL383987 | 0.82 | ELANE (0.48) | DPP4ELANEHTR2CSCN4ACYP1A2 | |
| SCHEMBL28789391 | 0.82 | ELANE (0.48) | DPP4ELANEHTR2CSCN4ACYP1A2 | |
| SCHEMBL21385077 | 0.81 | ELANE (0.47) | DPP4ELANEHTR2CSCN4ACYP1A2 | |
| SCHEMBL10903756 | 0.81 | DPP4 (0.47) | ALDH1A1DPP4ELANENPC1RAB9A | |
| SCHEMBL8691039 | 0.81 | CTSC (0.45) | DPP4NPC1RAB9AHRH2HRH1 | |
| SCHEMBL21646169 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL475274 | 0.73 | ALDH1A1 (0.69) | ALDH1A1PARP10PARP3ADRB2ADRB1 | |
| SCHEMBL146828 | 0.73 | NOS2 (0.46) | DPP4ELANESCN4ADPP8 | |
| SCHEMBL6859669 | 0.73 | NOS2 (0.46) | DPP4ELANESCN4ADPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018129-A1 | COMPOUNDS AS PU. 1 INHIBITORS | S-Infinity Pharmaceuticals (CN) | 2024-01-18 | — | — | US | disclosed |
| CN-117203198-A | Compounds as PU.1 inhibitors | 浙江星浩澎博医药有限公司 | 2023-12-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018129-A1 | COMPOUNDS AS PU. 1 INHIBITORS | FLI1, MCL1, SP1 | ALDH1A1 312/4885DPP4 3145/4885ELANE 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.