Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A9 | P06702 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271252 | 0.82 | CCR4 (0.38) | TSHRNPSR1CCR2KMT2ASMN1; SMN2 | |
| SCHEMBL271872 | 0.81 | SCD (0.42) | TSHRNPSR1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL270233 | 0.81 | ALDH1A1 (0.39) | S100A9TSHRCCR2MEN1KMT2A | |
| SCHEMBL307452 | 0.81 | CCR2 (0.58) | CCR2MEN1KMT2A | |
| SCHEMBL271678 | 0.81 | S1PR4 (0.42) | TSHRNPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL270245 | 0.79 | ALDH1A1 (0.37) | TSHRCCR2KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL270112 | 0.79 | ACLY (0.37) | TSHRCCR2MEN1KMT2ASCD | |
| SCHEMBL270266 | 0.78 | MCL1 (0.41) | MEN1KMT2ANOTUMKDM4E | |
| SCHEMBL270187 | 0.78 | CCR4 (0.44) | TSHRMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL271821 | 0.78 | NOTUM (0.39) | TSHRCCR2NOTUMKDM4ESCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | S100A9 3770/4885TSHR 1296/4885NPSR1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.