SCHEMBL271872

SCHEMBL271872

COC(=O)c1nccnc1NS(=O)(=O)Cc1c(Cl)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.42
CCR4 P51679 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GRM4 Q14833 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 2/20 0.37
TSHR P16473 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ABL1 P00519 1/20 0.37
SRC P12931 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272250 0.90 RORC (0.41) SCDCCR4ALDH1A1KMT2APOLB
SCHEMBL271252 0.89 CCR4 (0.38) SCDCCR4ALDH1A1KMT2APOLB
SCHEMBL270187 0.87 CCR4 (0.44) SCDCCR4ALDH1A1KMT2AGRM4
SCHEMBL271264 0.85 L3MBTL1 (0.37) SCDALDH1A1KMT2APOLBCYP1A2
SCHEMBL163954 0.84 KMT2A (0.43) ALDH1A1KMT2APOLBCYP1A2CYP2C9
SCHEMBL271821 0.84 NOTUM (0.39) SCDALDH1A1POLBGRM4KDM4E
SCHEMBL272346 0.83 ALDH1A1 (0.37) SCDALDH1A1POLBGRM4SMN1; SMN2
SCHEMBL272019 0.83 PTGDR2 (0.37) CCR4KMT2AGAAL3MBTL1
SCHEMBL270112 0.83 ACLY (0.37) SCDCCR4ALDH1A1KMT2APOLB
SCHEMBL271334 0.82 ACLY (0.38) SCDCCR4ALDH1A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220056-B1 HERBICIDAL COMPOUNDS SYNGENTA LTD (GB) 2015-09-30 EP disclosed
US-8133849-B2 Herbicidal compounds SYNGENTA LIMITED (GB) 2012-03-13 US disclosed
US-20100323889-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323889-A1 HERBICIDAL COMPOUNDS CBR3, DDT, CBR1 SCD 3715/4885CCR4 2864/4885ALDH1A1 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.