SCHEMBL27140346

SCHEMBL27140346

Fc1c(Cl)cc(Cl)cc1Nc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.49
GAA P10253 4/20 0.49
TDP1 Q9NUW8 4/20 0.49
ALOX15 P16050 3/20 0.49
HTT P42858 2/20 0.49
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
ACLY P53396 2/20 0.40
CXCR2 P25025 1/20 0.40
MEN1 O00255 6/20 0.39
MAPT P10636 6/20 0.39
KMT2A Q03164 6/20 0.39
KDM4E B2RXH2 4/20 0.39
GLA P06280 2/20 0.39
RECQL P46063 1/20 0.39
HSD17B10 Q99714 3/20 0.39
AR P10275 1/20 0.39
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27145734 0.81 ALDH1A1 (0.49) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL9629044 0.81 ALDH1A1 (0.52) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL9631014 0.75 ALDH1A1 (0.69) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL6669652 0.75 ALDH1A1 (0.53) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL22934022 0.75 ALDH1A1 (0.48) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL9630026 0.74 HSD17B10 (0.48) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL14315671 0.73 ALDH1A1 (0.67) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL26894571 0.72 L3MBTL1 (0.59) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL15791720 0.72 GAA (0.65) ALDH1A1GAATDP1ALOX15HTT
SCHEMBL18434217 0.72 L3MBTL1 (0.54) ALDH1A1GAATDP1ALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2024-07-04 US disclosed
EP-4326704-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS The University of Stavanger (NO) 2024-02-28 EP disclosed
WO-2022223390-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS DDT, DDC, CTRC ALDH1A1 1873/4885GAA 452/4885TDP1 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.