SCHEMBL27140347

SCHEMBL27140347

Fc1ccccc1Nc1cc(Cl)cc(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
ALDH1A1 P00352 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51
CYP2C19 P33261 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
EPAS1 Q99814 2/20 0.50
FADS1 O60427 1/20 0.43
MAPK10 P53779 1/20 0.43
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
PTK6 Q13882 1/20 0.42
APEX1 P27695 1/20 0.42
CDC25B P30305 1/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
CXCR2 P25025 1/20 0.41
GAA P10253 1/20 0.41
GRIK1 P39086 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27145735 0.78 SOS1 (0.50) ALDH1A1EPAS1RAB9ANPC1GAA
SCHEMBL6351009 0.77 MEN1 (0.54) CYP1A2ALDH1A1CYP2C9CYP2C19L3MBTL1
SCHEMBL1704615 0.76 MAPT (0.56) CYP1A2ALDH1A1CYP2C9HPGDCYP2C19
SCHEMBL30785818 0.76 MAPT (0.56) CYP1A2ALDH1A1CYP2C9HPGDCYP2C19
SCHEMBL396120 0.75 CXCL8 (0.55) ALDH1A1HPGDMAPK10CDC25BRAB9A
SCHEMBL29793294 0.75 CXCL8 (0.55) ALDH1A1HPGDMAPK10CDC25BRAB9A
SCHEMBL16481437 0.73 TAS2R14 (0.51) ALDH1A1L3MBTL1RAB9AGAASMN1; SMN2
SCHEMBL11178333 0.72 SMN1; SMN2 (0.56) HPGDMAPK10RAB9ANPC1GAA
SCHEMBL15129488 0.72 TSHR (0.48) ALDH1A1HPGDMAPK10CDC25BRAB9A
SCHEMBL22923289 0.72 MAPK10 (0.47) CYP1A2ALDH1A1CYP2C9HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2024-07-04 US disclosed
EP-4326704-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS The University of Stavanger (NO) 2024-02-28 EP disclosed
WO-2022223390-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS DDT, DDC, CTRC CYP1A2 327/4885ALDH1A1 1873/4885CYP2C9 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.