SCHEMBL27140396

SCHEMBL27140396

c1ccc2nc(CN3CCCCC3)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.57
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 3/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
HTR1A P08908 1/20 0.50
HTR7 P34969 1/20 0.50
HTT P42858 1/20 0.50
DRD4 P21917 1/20 0.48
PDE2A O00408 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
MCHR1 Q99705 1/20 0.46
GRIN2B Q13224 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6584608 0.93 FAAH (0.60) FAAHKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1331198 0.91 FAAH (0.65) FAAHHTR1AHTR7DRD4MCHR1
SCHEMBL17289123 0.91 FAAH (0.65) FAAHHTR1AHTR7DRD4MCHR1
SCHEMBL13940592 0.86 HRH3 (0.58) FAAHHTR1AHTR7DRD4PDE2A
SCHEMBL28824423 0.85 FAAH (0.56) FAAHHTR1AHTR7DRD4PDE2A
SCHEMBL6583960 0.85 CXCR4 (0.65) FAAHKDM4EALDH1A1HSD17B10HTR1A
SCHEMBL1331611 0.83 FAAH (0.58) FAAHKDM4EALDH1A1HTR1AHTR7
SCHEMBL1331766 0.83 HRH3 (0.63) FAAHHTR1AHTR7DRD4MCHR1
SCHEMBL21066574 0.83 CXCR4 (0.65) FAAHKDM4EALDH1A1HPGDHSD17B10
SCHEMBL2170401 0.83 CYP3A4 (0.55) FAAHKDM4EALDH1A1HSD17B10HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105218588-A A kind of preparation method and application of pyridyl benzoglyoxaline phenylquinoline iridium (III) title complex based on Long carbon chain modification UNIV NANJING POSTS & TELECOMM 2016-01-06 CN claimed
CN-104910213-A Phenyl quinoline derivative iridium (III) complex based on piperidine or morpholine methylene substitution, and preparation method and application thereof UNIV NANJING POSTS & TELECOMM 2015-09-16 CN claimed
US-20250186981-A1 CATALYST COMPOSITION FOR CYCLIC OLEFIN POLYMERIZATION, AND METHOD FOR PREPARING CYCLIC OLEFIN-BASED OLIGOMER OR OLEFIN-BASED POLYMER BY USING SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2025-06-12 US disclosed
US-20240294705-A1 TRANSITION METAL COMPLEX CATALYST COMPOSITION FOR POLYMERIZATION OF MONOMER HAVING CYCLIC ESTER GROUP AND METHOD OF PRODUCING POLYMER USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2024-09-05 US disclosed
US-20240245670-A1 DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES NOVARTIS AG (CH) 2024-07-25 US disclosed
WO-2024043542-A1 CATALYST COMPOSITION FOR CYCLIC OLEFIN POLYMERIZATION, AND METHOD FOR PREPARING CYCLIC OLEFIN-BASED OLIGOMER OR OLEFIN-BASED POLYMER BY USING SAME 경북대학교 산학협력단 2024-02-29 WO disclosed
CN-104910213-B A kind of phenylchinoline derivative iridium (III) complex substituted based on piperidines or morpholine methylene and its preparation method and application 南京邮电大学 2018-05-18 CN disclosed
CN-103664876-B Quinoline derivatives and uses thereof SUZHOU SOUTHEAST PHARMACEUTICALS CO., LTD. (CN) 2016-04-20 CN disclosed
CN-105218588-A A kind of preparation method and application of pyridyl benzoglyoxaline phenylquinoline iridium (III) title complex based on Long carbon chain modification UNIV NANJING POSTS & TELECOMM 2016-01-06 CN disclosed
CN-104910213-A Phenyl quinoline derivative iridium (III) complex based on piperidine or morpholine methylene substitution, and preparation method and application thereof UNIV NANJING POSTS & TELECOMM 2015-09-16 CN disclosed
CN-103772353-A Quinoline and application thereof UNIV SOUTHEAST 2014-05-07 CN disclosed
CN-103664876-A Quinoline derivative and usage thereof SOUTHEAST PHARMACEUTICALS CO LTD 2014-03-26 CN disclosed
CN-1019973-C Piperidine derivative and pharmaceutical composition containing the same EISAI CO LTD (JP) 1993-03-03 CN disclosed
CN-87100928-A Piperidine derivatives and pharmaceutical compositions thereof 1987-09-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245670-A1 DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES IKZF1, IKZF2, IKZF3 FAAH 4867/4885KDM4E 345/4885ALDH1A1 2942/4885
US-20240294705-A1 TRANSITION METAL COMPLEX CATALYST COMPOSITION FOR POLYMERIZATION OF MONOMER HAVING CYCLIC ESTER GROUP AND METHOD OF PRODUCING POLYMER USING THE SAME AP3M1, AP2M1, CAD FAAH 2948/4885KDM4E 786/4885ALDH1A1 3522/4885
US-20250186981-A1 CATALYST COMPOSITION FOR CYCLIC OLEFIN POLYMERIZATION, AND METHOD FOR PREPARING CYCLIC OLEFIN-BASED OLIGOMER OR OLEFIN-BASED POLYMER BY USING SAME PPOX, COG7, ODC1 FAAH 734/4885KDM4E 4231/4885ALDH1A1 2763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.