Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140139 | 0.79 | COMT (0.38) | ALDH1A1KDM4E | |
| SCHEMBL30782338 | 0.77 | TNF (0.46) | DRD2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL21068502 | 0.76 | DRD2 (0.56) | DRD2ALDH1A1TSHRCD274 | |
| SCHEMBL24213508 | 0.75 | KDM4E (0.40) | DRD2MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL12283967 | 0.75 | CYP2C9 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL31607756 | 0.73 | DRD2 (0.41) | DRD2CACNA1HMEN1ALDH1A1TSHR | |
| SCHEMBL31607750 | 0.73 | DRD2 (0.41) | DRD2CACNA1HMEN1KMT2ASIGMAR1 | |
| SCHEMBL25279192 | 0.73 | CACNA1H (0.56) | DRD2CACNA1HMEN1ALDH1A1TSHR | |
| SCHEMBL27139330 | 0.73 | HDAC6 (0.42) | DRD2MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL31301242 | 0.71 | DRD2 (0.63) | DRD2CACNA1HMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |