Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31607750 | 0.80 | DRD2 (0.41) | DRD2DRD3SIGMAR1CACNA1HMEN1 | |
| SCHEMBL27139330 | 0.75 | HDAC6 (0.42) | DRD2DRD3SIGMAR1ADORA1MEN1 | |
| SCHEMBL30782338 | 0.75 | TNF (0.46) | DRD2DRD3SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL27140818 | 0.73 | DRD2 (0.44) | DRD2SIGMAR1CACNA1HMEN1ALDH1A1 | |
| SCHEMBL30945677 | 0.70 | DRD2 (0.65) | DRD2SIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL21214308 | 0.70 | DRD2 (0.55) | DRD2SIGMAR1CACNA1HJAK2JAK1 | |
| SCHEMBL13975920 | 0.69 | DRD2 (0.50) | DRD2SIGMAR1CACNA1H | |
| SCHEMBL12507566 | 0.69 | DRD2 (0.53) | DRD2DRD3SIGMAR1 | |
| SCHEMBL21068502 | 0.69 | DRD2 (0.56) | DRD2ALDH1A1TSHR | |
| SCHEMBL24172673 | 0.69 | DRD2 (0.56) | DRD2SIGMAR1CACNA1HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |