Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782330 | 0.91 | DRD2 (0.48) | HSD17B10DRD2MEN1KMT2ADRD3 | |
| SCHEMBL30782283 | 0.87 | DRD2 (0.45) | HSD17B10DRD2MEN1KMT2ADRD3 | |
| SCHEMBL27149832 | 0.87 | DRD2 (0.45) | HSD17B10DRD2MEN1KMT2ADRD3 | |
| SCHEMBL27142595 | 0.82 | DRD2 (0.48) | DRD2CD274 | |
| SCHEMBL31607750 | 0.81 | DRD2 (0.41) | DRD2MEN1KMT2ADRD3SIGMAR1 | |
| SCHEMBL30945677 | 0.81 | DRD2 (0.65) | KDM4EALDH1A1MAPK1HSD17B10MAPT | |
| SCHEMBL27139330 | 0.80 | HDAC6 (0.42) | KDM4EALDH1A1MAPK1MAPTDRD2 | |
| SCHEMBL30782322 | 0.80 | ALDH1A1 (0.51) | TNFNOD1KDM4EALDH1A1MAPK1 | |
| SCHEMBL27146741 | 0.80 | ALDH1A1 (0.51) | TNFNOD1KDM4EALDH1A1MAPK1 | |
| SCHEMBL1648607 | 0.78 | NR1H2 (0.63) | KDM4EALDH1A1MAPK1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |