Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27136972 | 0.86 | KDM4E (0.43) | KMT2AALDH1A1 | |
| SCHEMBL31607759 | 0.67 | NOTUM (0.34) | ALDH1A1HRH3 | |
| SCHEMBL27152453 | 0.63 | AOC3 (0.37) | MEN1KMT2AALDH1A1GABRPGABRD | |
| SCHEMBL27151143 | 0.63 | PDE5A (0.35) | DPP4DPP8MEN1KMT2AALDH1A1 | |
| SCHEMBL26795412 | 0.62 | GRM5 (0.38) | GRM5GABRG2GABRB3GABRA5KCNH2 | |
| SCHEMBL27141027 | 0.62 | ALDH1A1 (0.40) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL27140550 | 0.62 | ALDH1A1 (0.46) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL20321444 | 0.61 | DHPS (0.46) | GRM5MEN1KMT2AALDH1A1KCNH2 | |
| SCHEMBL70795 | 0.61 | SMN1; SMN2 (0.65) | MEN1KMT2AALDH1A1GABRPGABRD | |
| SCHEMBL8132478 | 0.61 | SLC9A1 (0.62) | MEN1KMT2AALDH1A1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-120091998-A | Substituted bicyclic rings as HSET inhibitors | 默克专利股份公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |