Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27131627 | 1.00 | FKBP1A (0.37) | FKBP1ACA2CA12CA1CA9 | |
| SCHEMBL10452369 | 0.93 | CA2 (0.37) | CA2CA12CA1CA9LMNA | |
| SCHEMBL9628663 | 0.74 | KMT2A (0.39) | CA2CA12CA1CA9MMP1 | |
| SCHEMBL8602508 | 0.74 | MEN1 (0.33) | HSD17B10MGLLGAAKDM4EMAPT | |
| SCHEMBL27131193 | 0.73 | KDM4E (0.33) | LMNAHSD17B10KDM4EMAPTMAPK1 | |
| SCHEMBL8564925 | 0.73 | RAB9A (0.37) | HSD17B10MGLLGAAKDM4EMAPT | |
| SCHEMBL9626662 | 0.73 | SLC12A2 (0.37) | CA12CA1CA9LMNAHSD17B10 | |
| SCHEMBL27032127 | 0.73 | SLC12A2 (0.37) | CA12CA1CA9LMNAHSD17B10 | |
| SCHEMBL27031979 | 0.73 | SLC12A2 (0.37) | CA12CA1CA9LMNAHSD17B10 | |
| SCHEMBL27130489 | 0.73 | SLC12A2 (0.37) | CA12CA1CA9LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308570-A1 | MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2024-01-24 | — | — | EP | disclosed |