Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.52 |
| ▸ | GRM8 | O00222 | 2/20 | 0.52 |
| ▸ | GRM6 | O15303 | 2/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL2507758 | 1.00 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL7991504 | 0.86 | SLC1A1 (0.61) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| Succinic Acid SCHEMBL7991499 | 0.86 | SLC1A1 (0.61) | SLC1A1SLC1A2SLC1A3GRIK1GRIK2 | |
| Butyric Acid SCHEMBL31699640 | 0.84 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL17941814 | 0.84 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Dodecanoate SCHEMBL25310996 | 0.84 | GPR84 (0.63) | CYP1A2ALDH1A1ALOX15BLMKMT2A | |
| Myristic Acid SCHEMBL27890892 | 0.84 | GPR84 (0.63) | CYP1A2ALDH1A1ALOX15BLMKMT2A | |
| Palmitic Acid SCHEMBL28927197 | 0.84 | GPR84 (0.63) | CYP1A2ALDH1A1ALOX15BLMKMT2A | |
| Octanoic Acid SCHEMBL26624656 | 0.84 | GPR84 (0.63) | CYP1A2ALDH1A1ALOX15BLMKMT2A | |
| Decanoic Acid SCHEMBL13279587 | 0.84 | GPR84 (0.63) | CYP1A2ALDH1A1ALOX15BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207213-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS WITH ORAL SYSTEMICALLY BIOAVAILABLE BUTYRATE CONJUGATES | THE UNIVERSITY OF CHICAGO | 2024-06-27 | — | — | US | disclosed |
| EP-4326232-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS WITH ORAL SYSTEMICALLY BIOAVAILABLE BUTYRATE CONJUGATES | The University of Chicago (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022226482-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS WITH ORAL SYSTEMICALLY BIOAVAILABLE BUTYRATE CONJUGATES | THE UNIVERSITY OF CHICAGO (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207213-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS WITH ORAL SYSTEMICALLY BIOAVAILABLE BUTYRATE CONJUGATES | HBB, SI, FABP2 | FFAR3 31/4885HDAC3 486/4885HDAC1 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.