SCHEMBL27154154

SCHEMBL27154154

[CH2]c1cc2c(cn1)CNC2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627699 0.73 MB (0.31)
SCHEMBL20392716 0.73 CHRNA7 (0.39) PNMT
SCHEMBL15232148 0.73 NOS3 (0.54)
SCHEMBL29971347 0.73 CHRNB2 (0.42) PNMT
SCHEMBL903474 0.73 CHRNB2 (0.42) PNMT
Hydrochloric Acid SCHEMBL21800235 0.71 PNMT (0.34) PNMT
Hydrochloric Acid SCHEMBL31013974 0.71 NOS3 (0.52)
Hydrochloric Acid SCHEMBL31348244 0.71 CHRNA7 (0.38)
Hydrochloric Acid SCHEMBL20379721 0.71 CHRNB2 (0.41) PNMT
SCHEMBL3875704 0.68 TRPV4 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed