SCHEMBL2715526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18266254	0.93	MEN1 (0.41)	HSD17B13ADORA2AGLSTGFBR1TGFBR2
	SCHEMBL2715988	0.87	SCN9A (0.51)	HSD17B13ADORA2AGLSADORA3ADORA1
	SCHEMBL2715941	0.86	TGFBR1 (0.51)	HSD17B13ADORA2AGLSTGFBR1TGFBR2
	SCHEMBL2719487	0.85	MEN1 (0.41)	HSD17B13ADORA2ATGFBR1TGFBR2MEN1
	SCHEMBL2714095	0.82	KMT2A (0.56)	MEN1LMNAKMT2ARAB9ATDP1
	SCHEMBL26790250	0.78	ADORA2A (0.49)	HSD17B13ADORA2AGLSLMNAPOLB
	SCHEMBL18266380	0.78	KMT2A (0.47)	ADORA2AMEN1LMNAKMT2ANPC1
	SCHEMBL2714267	0.78	RIPK1 (0.48)	HSD17B13ADORA2AADORA3ADORA1EPHX2
	SCHEMBL2716839	0.78	GLS (0.41)	GLSMEN1LMNAKMT2ANPC1
	SCHEMBL2715895	0.77	MAPK14 (0.55)	GLS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.