SCHEMBL2719487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2713433	0.91	RIPK1 (0.41)	SCN9ASCN5AEPHX2HSD17B13
	SCHEMBL2717414	0.88	SCN9A (0.39)	SCN9ASCN5AEPHX2NPC1RAB9A
	SCHEMBL2715645	0.88	SCN9A (0.51)	MEN1KMT2ASCN9ASCN5AEPHX2
	SCHEMBL2717313	0.88	MEN1 (0.44)	MEN1LMNAKMT2ASCN9ASCN5A
	SCHEMBL2715526	0.85	HSD17B13 (0.48)	MEN1LMNAKMT2AEPHX2ADORA3
	SCHEMBL2716954	0.85	EPHX2 (0.45)	MEN1KMT2ASCN9AEPHX2ADORA3
	SCHEMBL2717677	0.83	PTGES (0.45)	SCN9AEPHX2
	SCHEMBL2716839	0.83	GLS (0.41)	MEN1LMNAKMT2ASCN9AEPHX2
	SCHEMBL2715667	0.83	EPHX2 (0.40)	LMNASCN9AEPHX2ADORA3ADORA1
	SCHEMBL2715291	0.83	EPHX2 (0.43)	SCN9ASCN5AEPHX2ADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.