Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124868 | 0.82 | SYK (0.38) | TDP1 | |
| SCHEMBL28164597 | 0.81 | ADORA3 (0.35) | LMNAALDH1A1GABRR1ADORA3 | |
| SCHEMBL13828436 | 0.80 | XDH (0.36) | — | |
| SCHEMBL18670632 | 0.78 | LMNA (0.33) | LMNABRD4ALDH1A1GABRR1 | |
| SCHEMBL23982374 | 0.72 | CDK1 (0.45) | LMNATDP1HPGDMEN1CYP1A2 | |
| SCHEMBL29654971 | 0.71 | BRD4 (0.40) | BRD4 | |
| SCHEMBL453219 | 0.71 | ABL1 (0.34) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22118770 | 0.71 | BRD4 (0.40) | BRD4 | |
| SCHEMBL16146526 | 0.71 | ADORA3 (0.43) | LMNAALDH1A1KDM4EADORA3 | |
| SCHEMBL18464405 | 0.70 | TSHR (0.50) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329773-A1 | PURINE NUCLEOSIDES, THEIR INTERMEDIATES, AND METHODS OF PREPARATION THEREOF | Astrocyte Pharmaceuticals, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |