Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29202360 | 1.00 | RBP4 (0.41) | RBP4PPARGSSTR1SSTR4KDM4E | |
| SCHEMBL29202347 | 0.87 | USP30 (0.44) | SSTR1SSTR4 | |
| SCHEMBL27158505 | 0.87 | USP30 (0.44) | SSTR1SSTR4 | |
| SCHEMBL25419344 | 0.75 | RBP4 (0.59) | RBP4SSTR1SSTR4TTRCHRNB2 | |
| SCHEMBL4259803 | 0.72 | EPHX2 (0.59) | RBP4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL25414530 | 0.72 | EPHX2 (0.59) | RBP4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL2946871 | 0.72 | EPHX2 (0.59) | RBP4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL30785512 | 0.72 | HDAC4 (0.41) | RBP4 | |
| SCHEMBL27158244 | 0.72 | HDAC4 (0.41) | RBP4 | |
| SCHEMBL30785518 | 0.72 | HTR2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |